| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 22-10-22 18:00 | Unión Santa Fé | Central Cordoba | 1:4 |
| 22-10-22 20:30 | Defensa y Justicia Florêncio Varela | Atlético Tucumán | 3:1 |
| 22-10-22 20:30 | CA San Lorenzo | CA Aldosivi | 3:0 |
| 22-10-22 20:30 | Estudiantes de La Plata | CD Godoy Cruz | 2:0 |
| 22-10-22 23:30 | Argentinos Juniors | CA Velez Sarsfield | 2:0 |
| 23-10-22 16:00 | CA Banfield | CA Sarmiento Junin | 0:0 |
| 23-10-22 18:30 | CA Talleres | Gimnasia y Esgrima La Plata | 2:1 |
| 23-10-22 21:00 | CA Patronato Paraná | CA Huracán | 3:2 |
| 23-10-22 21:00 | Racing Club | River Plate | 1:2 |
| 23-10-22 21:00 | Boca Juniors | Independiente | 2:2 |
| 24-10-22 19:30 | Barracas Central | Newell's Old Boys | 1:1 |
| 24-10-22 20:30 | Rosário Central | Club Atlético Colón | 1:1 |
| 25-10-22 0:30 | CA Tigre | Arsenal de Sarandi | 1:4 |
| 26-10-22 0:00 | CA Platense | CA Lanús | 1:1 |