Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 07-01-22 19:30 | 07-01-22 19:30 | FC Bayern Munique | Bor. Mönchengladbach | 1:2 | 1 - 3 pontos |
| 08-01-22 14:30 | 08-01-22 14:30 | SpVgg Greuther Fürth | VfB Estugarda | 0:0 | 1 - 3 pontos |
| 08-01-22 14:30 | 08-01-22 14:30 | 1899 Hoffenheim | FC Augsburg | 3:1 | 1 - 3 pontos |
| 08-01-22 14:30 | 08-01-22 14:30 | SC Friburgo | Arminia Bielefeld | 2:2 | 1 - 3 pontos |
| 08-01-22 14:30 | 08-01-22 14:30 | Bayer 04 Leverkusen | 1. FC Union Berlim | 2:2 | 1 - 3 pontos |
| 08-01-22 14:30 | 08-01-22 14:30 | RB Leipzig | FSV Mainz 05 | 4:1 | 1 - 3 pontos |
| 08-01-22 17:30 | 08-01-22 17:30 | Eintracht Frankfurt | Borussia Dortmund | 2:3 | 1 - 3 pontos |
| 09-01-22 14:30 | 09-01-22 14:30 | Hertha BSC Berlim | 1. FC Colónia | 1:3 | 1 - 3 pontos |
| 09-01-22 16:30 | 09-01-22 16:30 | VfL Bochum | VfL Wolfsburgo | 1:0 | 1 - 3 pontos |