| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 01-08-20 17:00 | Brescia Calcio | Sampdoria Génova | 1:1 |
| 01-08-20 19:45 | Juventus Turim | AS Roma | 1:3 |
| 01-08-20 19:45 | AC Milão | Cagliari Calcio | 3:0 |
| 01-08-20 19:45 | SSC Nápoles | Lazio Roma | 3:1 |
| 01-08-20 19:45 | Atalanta Bergamo | Inter Milão | 0:2 |
| 02-08-20 17:00 | SPAL Ferrara | AC Fiorentina | 1:3 |
| 02-08-20 19:45 | Sassuolo Calcio | Udinese Calcio | 0:1 |
| 02-08-20 19:45 | US Lecce | Parma Calcio 1913 | 3:4 |
| 02-08-20 19:45 | FC Génova 1893 | Hellas Verona | 3:0 |
| 02-08-20 19:45 | FC Bologna | FC Torino | 1:1 |