| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 20-05-22 18:00 | Antalyaspor | Galatasaray Istambul | 1:1 |
| 20-05-22 18:00 | Gazisehir Gaziantep FK | Caykur Rizespor | 2:0 |
| 21-05-22 14:00 | Altay SK | Kasimpasa Istambul | 2:4 |
| 21-05-22 14:00 | Sivasspor | Kayserispor | 2:1 |
| 21-05-22 17:00 | Besiktas Istambul | Konyaspor | 1:1 |
| 21-05-22 17:00 | Yeni Malatyaspor | Fenerbahce Istambul | 0:5 |
| 22-05-22 14:00 | Fatih Karagümrük | Alanyaspor | 0:1 |
| 22-05-22 14:00 | Istambul Basaksehir FK | Trabzonspor | 3:1 |
| 22-05-22 17:00 | Hatayspor | Giresunspor | 4:1 |
| 22-05-22 17:00 | Adana Demirspor | Göztepe Izmir | 7:0 |