| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|
| 07-01-22 19:30 | 07-01-22 19:00 | FC Bayern Munique | Bor. Mönchengladbach | 1:2 | 2 - 4 pontos |
| 08-01-22 14:30 | 08-01-22 14:00 | SpVgg Greuther Fürth | VfB Estugarda | 0:0 | 2 - 4 pontos |
| 08-01-22 14:30 | 08-01-22 14:00 | 1899 Hoffenheim | FC Augsburg | 3:1 | 2 - 4 pontos |
| 08-01-22 14:30 | 08-01-22 14:00 | SC Friburgo | Arminia Bielefeld | 2:2 | 2 - 4 pontos |
| 08-01-22 14:30 | 08-01-22 14:00 | Bayer 04 Leverkusen | 1. FC Union Berlim | 2:2 | 2 - 4 pontos |
| 08-01-22 14:30 | 08-01-22 14:00 | RB Leipzig | FSV Mainz 05 | 4:1 | 2 - 4 pontos |
| 08-01-22 17:30 | 08-01-22 17:00 | Eintracht Frankfurt | Borussia Dortmund | 2:3 | 2 - 4 pontos |
| 09-01-22 14:30 | 09-01-22 14:00 | Hertha BSC Berlim | 1. FC Colónia | 1:3 | 2 - 4 pontos |
| 09-01-22 16:30 | 09-01-22 16:00 | VfL Bochum | VfL Wolfsburgo | 1:0 | 2 - 4 pontos |
