| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|
| 05-08-22 19:35 | 05-08-22 19:05 | Eintracht Frankfurt | FC Bayern Munique | 1:6 | 2 - 4 pontos |
| 06-08-22 14:30 | 06-08-22 14:00 | FC Augsburg | SC Friburgo | 0:4 | 2 - 4 pontos |
| 06-08-22 14:30 | 06-08-22 14:00 | VfL Bochum | FSV Mainz 05 | 1:2 | 2 - 4 pontos |
| 06-08-22 14:30 | 06-08-22 14:00 | Bor. Mönchengladbach | 1899 Hoffenheim | 3:1 | 2 - 4 pontos |
| 06-08-22 14:30 | 06-08-22 14:00 | 1. FC Union Berlim | Hertha BSC Berlim | 3:1 | 2 - 4 pontos |
| 06-08-22 14:30 | 06-08-22 14:00 | VfL Wolfsburgo | Werder Bremen | 2:2 | 2 - 4 pontos |
| 06-08-22 17:30 | 06-08-22 17:00 | Borussia Dortmund | Bayer 04 Leverkusen | 1:0 | 2 - 4 pontos |
| 07-08-22 14:30 | 07-08-22 14:00 | VfB Estugarda | RB Leipzig | 1:1 | 2 - 4 pontos |
| 07-08-22 16:30 | 07-08-22 16:00 | 1. FC Colónia | FC Schalke 04 | 3:1 | 2 - 4 pontos |
