Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 06-05-22 19:30 | 06-05-22 19:29 | VfL Bochum | Arminia Bielefeld | 2:1 | 2 - 4 pontos |
| 07-05-22 14:30 | 07-05-22 14:29 | 1899 Hoffenheim | Bayer 04 Leverkusen | 2:4 | 2 - 4 pontos |
| 07-05-22 14:30 | 07-05-22 14:29 | SC Friburgo | 1. FC Union Berlim | 1:4 | 2 - 4 pontos |
| 07-05-22 14:30 | 07-05-22 14:29 | SpVgg Greuther Fürth | Borussia Dortmund | 1:3 | 2 - 4 pontos |
| 07-05-22 14:30 | 07-05-22 14:29 | 1. FC Colónia | VfL Wolfsburgo | 0:1 | 2 - 4 pontos |
| 07-05-22 17:30 | 07-05-22 17:29 | Hertha BSC Berlim | FSV Mainz 05 | 1:2 | 2 - 4 pontos |
| 08-05-22 14:30 | 08-05-22 14:29 | Eintracht Frankfurt | Bor. Mönchengladbach | 1:1 | 2 - 4 pontos |
| 08-05-22 16:30 | 08-05-22 16:29 | FC Bayern Munique | VfB Estugarda | 2:2 | 2 - 4 pontos |
| 08-05-22 18:30 | 08-05-22 18:29 | RB Leipzig | FC Augsburg | 4:0 | 2 - 4 pontos |