Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 19-04-22 18:00 | 19-04-22 18:00 | RCD Mallorca | Deportivo Alavés | 2:1 | 3 - 4 - 6 |
| 19-04-22 20:00 | 19-04-22 20:00 | Real Betis Sevilla | FC Elche | 0:1 | 3 - 6 - 6 |
| 19-04-22 20:30 | 19-04-22 20:30 | FC Villarreal | FC Valencia | 2:0 | 3 - 6 - 6 |
| 20-04-22 18:00 | 20-04-22 18:00 | Atlético Madrid | FC Granada | 0:0 | 3 - 6 - 6 |
| 20-04-22 19:00 | 20-04-22 19:00 | Celta Vigo | FC Getafe | 0:2 | 3 - 6 - 5 |
| 20-04-22 20:30 | 20-04-22 20:30 | CA Osasuna | Real Madrid | 1:3 | 6 - 6 - 3 |
| 21-04-22 18:00 | 21-04-22 18:00 | Espanyol Barcelona | Rayo Vallecano | 0:1 | 3 - 4 - 6 |
| 21-04-22 18:00 | 21-04-22 18:00 | UD Levante | FC Sevilla | 2:3 | 6 - 6 - 3 |
| 21-04-22 19:00 | 21-04-22 19:00 | FC Cádiz | Athletic Bilbao | 2:3 | 4 - 5 - 4 |
| 21-04-22 20:30 | 21-04-22 20:30 | Real Sociedad | FC Barcelona | 0:1 | 5 - 6 - 3 |