| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 23-10-24 15:30 | Sporting Braga | FK Bodö/Glimt | 1:2 |
| 23-10-24 15:30 | Galatasaray Istambul | IF Elfsborg Boras | 4:3 |
| 24-10-24 17:45 | AS Roma | Dínamo Kiev | 1:0 |
| 24-10-24 17:45 | Eintracht Frankfurt | Rigas Futbola Skola | 1:0 |
| 24-10-24 17:45 | Maccabi Tel Avive | Real Sociedad | 1:2 |
| 24-10-24 17:45 | Ferencvaros Budapest | OGC Nice | 1:0 |
| 24-10-24 17:45 | PAOK Salónica | Viktoria Plzeň | 2:2 |
| 24-10-24 17:45 | FC Midtjylland | Royale Union Saint-Gilloise | 1:0 |
| 24-10-24 17:45 | Qarabag | Ajax Amsterdão | 0:3 |
| 24-10-24 20:00 | Fenerbahce Istambul | Manchester United | 1:1 |
| 24-10-24 20:00 | Glasgow Rangers | FCSB Bukarest | 4:0 |
| 24-10-24 20:00 | FC Porto | 1899 Hoffenheim | 2:0 |
| 24-10-24 20:00 | Tottenham Hotspurs | AZ Alkmaar | 1:0 |
| 24-10-24 20:00 | Olympique Lyon | Besiktas Istambul | 0:1 |
| 24-10-24 20:00 | Malmö FF | Olympiakos Pireu | 0:1 |
| 24-10-24 20:00 | FC Twente Enschede | Lazio Roma | 0:2 |
| 24-10-24 20:00 | RSC Anderlecht | PFC Ludogorets Razgrad | 2:0 |
| 24-10-24 20:00 | Athletic Bilbao | Slavia Praga | 1:0 |