| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 21-01-25 15:30 | Galatasaray Istambul | Dínamo Kiev | 3:3 |
| 22-01-25 15:30 | Besiktas Istambul | Athletic Bilbao | -:- |
| 23-01-25 17:45 | AZ Alkmaar | AS Roma | -:- |
| 23-01-25 17:45 | Malmö FF | FC Twente Enschede | -:- |
| 23-01-25 17:45 | FK Bodö/Glimt | Maccabi Tel Avive | -:- |
| 23-01-25 17:45 | Qarabag | FCSB Bukarest | -:- |
| 23-01-25 17:45 | Viktoria Plzeň | RSC Anderlecht | -:- |
| 23-01-25 17:45 | 1899 Hoffenheim | Tottenham Hotspurs | -:- |
| 23-01-25 17:45 | FC Porto | Olympiakos Pireu | -:- |
| 23-01-25 17:45 | Fenerbahce Istambul | Olympique Lyon | -:- |
| 23-01-25 20:00 | Rigas Futbola Skola | Ajax Amsterdão | -:- |
| 23-01-25 20:00 | PFC Ludogorets Razgrad | FC Midtjylland | -:- |
| 23-01-25 20:00 | Royale Union Saint-Gilloise | Sporting Braga | -:- |
| 23-01-25 20:00 | IF Elfsborg Boras | OGC Nice | -:- |
| 23-01-25 20:00 | Eintracht Frankfurt | Ferencvaros Budapest | -:- |
| 23-01-25 20:00 | Manchester United | Glasgow Rangers | -:- |
| 23-01-25 20:00 | Lazio Roma | Real Sociedad | -:- |
| 23-01-25 20:00 | PAOK Salónica | Slavia Praga | -:- |