| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 11-12-24 15:30 | Fenerbahce Istambul | Athletic Bilbao | 0:2 |
| 12-12-24 17:45 | Malmö FF | Galatasaray Istambul | 2:2 |
| 12-12-24 17:45 | AS Roma | Sporting Braga | 3:0 |
| 12-12-24 17:45 | PAOK Salónica | Ferencvaros Budapest | 5:0 |
| 12-12-24 17:45 | Olympiakos Pireu | FC Twente Enschede | 0:0 |
| 12-12-24 17:45 | Royale Union Saint-Gilloise | OGC Nice | 2:1 |
| 12-12-24 17:45 | PFC Ludogorets Razgrad | AZ Alkmaar | 2:2 |
| 12-12-24 17:45 | Viktoria Plzeň | Manchester United | 1:2 |
| 12-12-24 17:45 | 1899 Hoffenheim | FCSB Bukarest | 0:0 |
| 12-12-24 20:00 | Glasgow Rangers | Tottenham Hotspurs | 1:1 |
| 12-12-24 20:00 | FC Porto | FC Midtjylland | 2:0 |
| 12-12-24 20:00 | Slavia Praga | RSC Anderlecht | 1:2 |
| 12-12-24 20:00 | Ajax Amsterdão | Lazio Roma | 1:3 |
| 12-12-24 20:00 | Maccabi Tel Avive | Rigas Futbola Skola | 2:1 |
| 12-12-24 20:00 | Real Sociedad | Dínamo Kiev | 3:0 |
| 12-12-24 20:00 | Olympique Lyon | Eintracht Frankfurt | 3:2 |
| 12-12-24 20:00 | FK Bodö/Glimt | Besiktas Istambul | 2:1 |
| 12-12-24 20:00 | IF Elfsborg Boras | Qarabag | 1:0 |