Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 20-08-21 19:30 | 20-08-21 19:30 | RB Leipzig | VfB Estugarda | 4:0 | 2 - 5 - 8 |
| 21-08-21 14:30 | 21-08-21 14:30 | SpVgg Greuther Fürth | Arminia Bielefeld | 1:1 | 4 - 3 - 3 |
| 21-08-21 14:30 | 21-08-21 14:30 | VfL Bochum | FSV Mainz 05 | 2:0 | 5 - 4 - 3 |
| 21-08-21 14:30 | 21-08-21 14:30 | SC Friburgo | Borussia Dortmund | 2:1 | 8 - 8 - 2 |
| 21-08-21 14:30 | 21-08-21 14:30 | Eintracht Frankfurt | FC Augsburg | 0:0 | 2 - 7 - 8 |
| 21-08-21 14:35 | 21-08-21 14:35 | Hertha BSC Berlim | VfL Wolfsburgo | 1:2 | 5 - 4 - 3 |
| 21-08-21 17:30 | 21-08-21 17:30 | Bayer 04 Leverkusen | Bor. Mönchengladbach | 4:0 | 3 - 4 - 4 |
| 22-08-21 14:30 | 22-08-21 14:30 | 1899 Hoffenheim | 1. FC Union Berlim | 2:2 | 2 - 6 - 7 |
| 22-08-21 16:30 | 22-08-21 16:30 | FC Bayern Munique | 1. FC Colónia | 3:2 | 2 - 8 - 8 |