Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 29-04-22 20:00 | 29-04-22 20:00 | FC Sevilla | FC Cádiz | 1:1 | 2 - 5 pontos |
| 30-04-22 13:00 | 30-04-22 13:00 | Deportivo Alavés | FC Villarreal | 2:1 | 2 - 5 pontos |
| 30-04-22 15:15 | 30-04-22 15:15 | Real Madrid | Espanyol Barcelona | 4:0 | 2 - 5 pontos |
| 30-04-22 17:30 | 30-04-22 17:30 | FC Valencia | UD Levante | 1:1 | 2 - 5 pontos |
| 30-04-22 20:00 | 30-04-22 20:00 | Athletic Bilbao | Atlético Madrid | 2:0 | 2 - 5 pontos |
| 01-05-22 13:00 | 01-05-22 13:00 | FC Elche | CA Osasuna | 1:1 | 2 - 5 pontos |
| 01-05-22 15:15 | 01-05-22 15:15 | FC Granada | Celta Vigo | 1:1 | 2 - 5 pontos |
| 01-05-22 17:30 | 01-05-22 17:30 | Rayo Vallecano | Real Sociedad | 1:1 | 2 - 5 pontos |
| 01-05-22 20:00 | 01-05-22 20:00 | FC Barcelona | RCD Mallorca | 2:1 | 2 - 5 pontos |
| 02-05-22 20:00 | 02-05-22 20:00 | FC Getafe | Real Betis Sevilla | 0:0 | 2 - 5 pontos |