Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 04-03-22 20:00 | 04-03-22 20:00 | Deportivo Alavés | FC Sevilla | 0:0 | 2 - 5 pontos |
| 05-03-22 13:00 | 05-03-22 13:00 | CA Osasuna | FC Villarreal | 1:0 | 2 - 5 pontos |
| 05-03-22 15:15 | 05-03-22 15:15 | Espanyol Barcelona | FC Getafe | 2:0 | 2 - 5 pontos |
| 05-03-22 17:30 | 05-03-22 17:30 | FC Valencia | FC Granada | 3:1 | 2 - 5 pontos |
| 05-03-22 20:00 | 05-03-22 20:00 | Real Madrid | Real Sociedad | 4:1 | 2 - 5 pontos |
| 06-03-22 13:00 | 06-03-22 13:00 | FC Cádiz | Rayo Vallecano | 2:0 | 2 - 5 pontos |
| 06-03-22 15:15 | 06-03-22 15:15 | FC Elche | FC Barcelona | 1:2 | 2 - 5 pontos |
| 06-03-22 17:30 | 06-03-22 17:30 | Celta Vigo | RCD Mallorca | 4:3 | 2 - 5 pontos |
| 06-03-22 20:00 | 06-03-22 20:00 | Real Betis Sevilla | Atlético Madrid | 1:3 | 2 - 5 pontos |
| 07-03-22 20:00 | 07-03-22 20:00 | Athletic Bilbao | UD Levante | 3:1 | 2 - 5 pontos |