Calendário
| Data | Prazo para submeter os prognósticos | Casa | Visitante | Resultado | Regra de pontuação |
|---|---|---|---|---|---|
| 30-10-21 13:00 | 30-10-21 13:00 | FC Elche | Real Madrid | 1:2 | 2 - 5 pontos |
| 30-10-21 15:15 | 30-10-21 15:15 | FC Sevilla | CA Osasuna | 2:0 | 2 - 5 pontos |
| 30-10-21 17:30 | 30-10-21 17:30 | FC Valencia | FC Villarreal | 2:0 | 2 - 5 pontos |
| 30-10-21 20:00 | 30-10-21 20:00 | FC Barcelona | Deportivo Alavés | 1:1 | 2 - 5 pontos |
| 31-10-21 13:00 | 31-10-21 13:00 | FC Cádiz | RCD Mallorca | 1:1 | 2 - 5 pontos |
| 31-10-21 15:15 | 31-10-21 15:15 | Atlético Madrid | Real Betis Sevilla | 3:0 | 2 - 5 pontos |
| 31-10-21 17:30 | 31-10-21 17:30 | FC Getafe | Espanyol Barcelona | 2:1 | 2 - 5 pontos |
| 31-10-21 20:00 | 31-10-21 20:00 | Real Sociedad | Athletic Bilbao | 1:1 | 2 - 5 pontos |
| 01-11-21 17:30 | 01-11-21 17:30 | Rayo Vallecano | Celta Vigo | 0:0 | 2 - 5 pontos |
| 01-11-21 20:00 | 01-11-21 20:00 | UD Levante | FC Granada | 0:3 | 2 - 5 pontos |